OSM Receptor
Rose T.M., Bruce A.G.
Oncostatin M (OSM), a member of the IL-6 family of cytokines, interacts with low-affinity receptor subunit monomers and high-affinity heterodimeric receptor complexes composed of members of the class I cytokine receptor family. Important species-specific differences in receptor binding have been identified. OSM binds directly with low-affinity to gpl30, which was originally characterized as the signal transducer sub-unit within the high-affinity IL-6 receptor complex.
Language:
english
Pages:
22
File:
PDF, 1.37 MB
IPFS:
,
english0
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